(S)-PI3K-IN-2

MedChem Express

(S)-PI3K-IN-2

5

Research Use Only

99.50

C28H29F2N3O5

525.54

(S)-PI3K-IN-2, an enantiomer of PI3K-IN-2 (HY-101517), is a Piota3kappabeta/delta inhibitor, with IC50s of 0.198 and 0.282 micromicro, respectively. (S)-PI3K-IN-2 can inhibit phospho AKT (ser473) in MDA-MB-468 cells (IC50=27 nM)[1].

O=C1C=C(N2CCOCC2)OC3=C([C@H]4N(C5=CC(F)=CC(F)=C5)CCC4)C=C(C(N6CCOCC6)=O)C=C13

-20°C,2°C to 8°C

12352200