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(S)-Thalidomide-piperazine-(1S,4r)-cyclohexane-N(Me)-Boc

HY-163221
MedChem Express
Product group Molecular Biology
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Overview

  • Supplier
    MedChem Express
  • Product Name
    (S)-Thalidomide-piperazine-(1S,4r)-cyclohexane-N(Me)-Boc
  • Delivery Days Customer
    14
  • Certification
    Research Use Only
  • Molecular Formula
    C30H41N5O6
  • Molecular Weight
    567.68
  • Scientific Description
    (S)-Thalidomide-piperazine-(1S,4r)-cyclohexane-N(Me)-Boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. (S)-Thalidomide-piperazine-(1S,4r)-cyclohexane-N(Me)-Boc can serve as Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
  • SMILES
    O=C1NC(CC[C@@H]1N2C(C3=C(C=CC(N4CCN(CC4)C[C@H]5CC[C@@H](CC5)N(C)C(OC(C)(C)C)=O)=C3)C2=O)=O)=O
  • UNSPSC
    41115800