S0859

MedChem Express

S0859 [1019331-10-2]

10

1019331-10-2

Research Use Only

99.69

C29H24ClN3O3S

530.04

S0859 is a selective, high-affinity generic Na + /HCO 3 - transporter ( NBC ) inhibitor. S0859 reversibly inhibits NBC-mediated intracellular pH (pHi) recovery (K i =1.7 microM, full inhibition at approximately 30 microM).

O=C(N(CC1=CC=C(C2=CC=CC=C2S(=O)(NC#N)=O)C=C1)CC3=CC=C(C)C=C3)C4=CC=CC=C4Cl

-20°C,2°C to 8°C

12352200