S100 alpha antibody
GTX11428
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Human, Mouse, Porcine, Rat
TargetS100A1
Overview
- SupplierGeneTex
- Product NameS100 alpha antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 0.1 microg/ml. ICC/IF: 1:50-1:200. IHC-P: 1 microg/ml. IP: 5 microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID6271
- Target nameS100A1
- Target descriptionS100 calcium binding protein A1
- Target synonymsS100, S100-alpha, S100A, protein S100-A1, S-100 protein alpha chain, S-100 protein subunit alpha, S100 alpha, S100 protein, alpha polypeptide
- HostRabbit
- IsotypeIgG
- Protein IDP23297
- Protein NameProtein S100-A1
- Scientific DescriptionThe protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies. [provided by RefSeq, Jul 2008]
- ReactivityBovine, Human, Mouse, Porcine, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Desjardins JF, Pourdjabbar A, Quan A, et al. Lack of S100A1 in mice confers a gender-dependent hypertensive phenotype and increased mortality after myocardial infarction. Am J Physiol Heart Circ Physiol. 2009,296(5):H1457-65. doi: 10.1152/ajpheart.00088.2008Read this paper

![Various tissue extracts (50 μg) were separated by 15% SDS-PAGE, and the membrane was blotted with S100 alpha antibody [GT1311] (GTX03223) diluted at 1:5000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.](https://www.genetex.com/upload/website/prouct_img/normal/GTX03223/GTX03223_4000000404_20210716_WB_M_tissue_w_23053123_893.webp)
![IHC-P analysis of human melanoma tissue using GTX34997 S100 alpha antibody [S1/61].](https://www.genetex.com/upload/website/prouct_img/normal/GTX34997/GTX34997_20200115_IHC-P_778_w_23060801_909.webp)


