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S130 [1160852-22-1]

S130 [1160852-22-1]

Research Use Only
T12819
TargetMol Chemicals
CAS Number1160852-22-1
Product group Chemicals
Molecular Weight387.47
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    S130 [1160852-22-1]
  • Delivery Days Customer
    72
  • CAS Number
    1160852-22-1
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    S130
  • Molecular Formula
    C24H25N3O2
  • Molecular Weight
    387.47
  • Scientific Description
    S130 is a high affinity, selectiveATG4B (a major cysteine protease) inhibitor (IC50 of 3.24 microM).It suppresses autophagy flux.
  • Shelf life instruction
    3 years
  • SMILES
    CCN(CC)CCCNC(=O)c1cnc2C(=O)c3ccccc3-c3cccc1c23
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Discovery of a small molecule targeting autophagy via ATG4B inhibition and cell death of colorectal cancer cells in vitro and in vivo. Fu Y et al., 2019 Feb, Autophagy
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