S130 [1160852-22-1]
T12819
CAS Number1160852-22-1
Product group Chemicals
Molecular Weight387.47
Overview
- SupplierTargetMol Chemicals
- Product NameS130 [1160852-22-1]
- Delivery Days Customer72
- CAS Number1160852-22-1
- CertificationResearch Use Only
- Chemical NameS130
- Molecular FormulaC24H25N3O2
- Molecular Weight387.47
- Scientific DescriptionS130 is a high affinity, selectiveATG4B (a major cysteine protease) inhibitor (IC50 of 3.24 microM).It suppresses autophagy flux.
- Shelf life instruction3 years
- SMILESCCN(CC)CCCNC(=O)c1cnc2C(=O)c3ccccc3-c3cccc1c23
- Storage Instruction-20°C
- UNSPSC12352200
References
- Fu Y, Hong L, Xu J, et al. Discovery of a small molecule targeting autophagy via ATG4B inhibition and cell death of colorectal cancer cells in vitro and in vivo. Autophagy. 2019,15(2):295-311. doi: 10.1080/15548627.2018.1517073Read this paper
MSDS
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