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ProductsBack/S1RA (hydrochloride) [1265917-14-3]

S1RA (hydrochloride) [1265917-14-3]

Research Use Only
HY-18099A
MedChem Express
CAS Number1265917-14-3
DownloadMSDS
Product group Chemicals
Estimated Purity99.94
Molecular Weight373.88
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Overview

  • Supplier
    MedChem Express
  • Product Name
    S1RA (hydrochloride) [1265917-14-3]
  • Delivery Days Customer
    9
  • CAS Number
    1265917-14-3
  • Certification
    Research Use Only
  • Estimated Purity
    99.94
  • Molecular Formula
    C20H24ClN3O2
  • Molecular Weight
    373.88
  • Scientific Description
    S1RA (E-52862) hydrochloride is an orally active and selective sigma-1 receptor (sigma1R) antagonist with a Ki value of 17 nM. S1RA hydrochloride shows good selectivity against sigma2R (Ki >1000 nM). S1RA hydrochloride is a human 5-HT2B receptor antagonist with an IC50 value of 4.7 microM. S1RA hydrochloride inhibits neuropathic pain and activity-induced spinal sensitization[1][2].
  • SMILES
    CC1=CC(OCCN2CCOCC2)=NN1C3=CC(C=CC=C4)=C4C=C3.[H]Cl
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200