S65487 [1644600-79-2]

TargetMol Chemicals

S65487 [1644600-79-2]

10

1644600-79-2

Chemical

Research Use Only

S65487

C41H41ClN6O4

717.26

S65487 (VOB560) is a potent and selective Bcl-2 inhibitor. S65487 is also active on BCL-2 mutations, such as G101V and D103Y. S65487 has poor affinity with MCL-1, BFL-1 and BCL-XL. S65487 induces apoptosis and has anticaner activities[1][2].

3 years

Cc1c(cc(C#N)n1C)N(C(=O)c1cc(-c2cc(Cl)ccc2C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)n(C)c1C)c1ccc(O)cc1

-20°C

12352200