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ProductsBack/SA09-Cu [155641-16-0]

SA09-Cu [155641-16-0]

HY-150260
MedChem Express
CAS Number155641-16-0
DownloadMSDS
Product group Chemicals
Molecular Weight364.03
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Overview

  • Supplier
    MedChem Express
  • Product Name
    SA09-Cu [155641-16-0]
  • Delivery Days Customer
    10
  • CAS Number
    155641-16-0
  • Certification
    Research Use Only
  • Molecular Formula
    C8H16CuN2O2S4
  • Molecular Weight
    364.03
  • Scientific Description
    SA09-Cu is a noncompetitive and potent NDM-1 inhibitor with an IC50 of 9.6 nM. SA09-Cu can convert NDM-1 into an inactive state by oxidizing the Zn(II)-thiolate site of the enzyme and avoids to be reduced by intracellular thiols of bacteria. SA09-Cu exhibits excellent inhibition against a series of clinical NDM-1-producing carbapenem-resistant Enterobacteriaceae (CRE) in restoring the Meropenem (HY-13678) effect, and slows down the development of carbapenem resistance[1].
  • SMILES
    OCCN(C)C1=[S-][Cu+2]2(SC(N(C)CCO)=[S-]2)S1
  • UNSPSC
    12131703