SA57 [1346169-63-8]

MedChem Express

SA57 [1346169-63-8]

10

1346169-63-8

Research Use Only

99.0

C17H23ClN2O3

338.83

SA57 is a potent, selective FAAH inhibitor with IC50s of 3.2 nM and 1.9 nM for mouse and human FAAH. SA57 also inhibits the 2-arachidonoylglycerol hydrolases MAGL (IC50s of 410 nM and 1.4 microM for mouse and human MAGL) and mouse alpha/beta-hydrolase domain-containing protein 6 (mABHD6; IC50 of 850 nM), but not other brain serine hydrolases[1][2].

O=C(N1CCC(CCC2=CC=C(Cl)C=C2)CC1)OCC(NC)=O

-20°C

12352200