Sabizabulin (hydrochloride) [2635953-17-0]
HY-120599A
CAS Number2635953-17-0
Product group Chemicals
Molecular Weight413.85
Overview
- SupplierMedChem Express
- Product NameSabizabulin (hydrochloride) [2635953-17-0]
- Delivery Days Customer9
- CAS Number2635953-17-0
- CertificationResearch Use Only
- Molecular FormulaC21H20ClN3O4
- Molecular Weight413.85
- Scientific DescriptionSabizabulin hydrochloride is a potent orally bioavailable microtubule inhibitor with activity that interacts with the colchicine binding site. Sabizabulin hydrochloride demonstrated significant inhibition of melanoma tumor growth with an average IC50 of 5.2 nM in melanoma and prostate cancer cell lines. Pharmacological screening of Sabizabulin hydrochloride shows it has a low risk of potential side effects[1].
- SMILESO=C(C1=CN=C(C2=CNC3=C2C=CC=C3)N1)C4=CC(OC)=C(C(OC)=C4)OC.Cl
- UNSPSC12352200