Saclofen [125464-42-8]
HY-100813
CAS Number125464-42-8
Product group Chemicals
Estimated Purity99.70
Molecular Weight249.72
Overview
- SupplierMedChem Express
- Product NameSaclofen [125464-42-8]
- Delivery Days Customer10
- CAS Number125464-42-8
- CertificationResearch Use Only
- Estimated Purity99.70
- Molecular FormulaC9H12ClNO3S
- Molecular Weight249.72
- Scientific DescriptionSaclofen is an orally active and a competitive GABAB receptor antagonist with an IC50 of 7.8 microM. Saclofen has weak antagonistic effects on GABAB1b and GABAB2 heterodimeric recombinant receptors. Saclofen inhibits the binding of Baclofen (HY-B0007) to rat cerebellar membranes and blocks Baclofen-induced circadian phase shifts, and exhibits anti-inflammatory and analgesic effects in rats[1][2][3][4][5].
- SMILESO=S(CC(CN)C1=CC=C(Cl)C=C1)(O)=O
- Storage Instruction-20°C
- UNSPSC12352200
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