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Saclofen [125464-42-8]

HY-100813
MedChem Express
CAS Number125464-42-8
Product group Chemicals
Estimated Purity99.70
Molecular Weight249.72
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Saclofen [125464-42-8]
  • Delivery Days Customer
    10
  • CAS Number
    125464-42-8
  • Certification
    Research Use Only
  • Estimated Purity
    99.70
  • Molecular Formula
    C9H12ClNO3S
  • Molecular Weight
    249.72
  • Scientific Description
    Saclofen is an orally active and a competitive GABAB receptor antagonist with an IC50 of 7.8 microM. Saclofen has weak antagonistic effects on GABAB1b and GABAB2 heterodimeric recombinant receptors. Saclofen inhibits the binding of Baclofen (HY-B0007) to rat cerebellar membranes and blocks Baclofen-induced circadian phase shifts, and exhibits anti-inflammatory and analgesic effects in rats[1][2][3][4][5].
  • SMILES
    O=S(CC(CN)C1=CC=C(Cl)C=C1)(O)=O
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200