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Saclofen

HY-100813
MedChem Express
CAS Number125464-42-8
Product group Chemicals
Estimated Purity99.87
Molecular Weight249.719
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Saclofen [125464-42-8]
  • Delivery Days Customer
    10
  • CAS Number
    125464-42-8
  • Certification
    Research Use Only
  • Estimated Purity
    99.87
  • Molecular Formula
    C9H12ClNO3S
  • Molecular Weight
    249.719
  • Scientific Description
    Saclofen is an orally available competitive GABA B receptor antagonist with an IC 50 of 7.8 microM, but it has a weaker antagonistic effect on GABA B1b and GABA B2 heterodimer recombinant receptors. Saclofen can inhibit the binding of baclofen (HY-B007) to rat cerebellar membranes and block the phase shifts in circadian rhythms caused by baclofen. Saclofen has also shown anti-inflammatory and analgesic effects in rats [1] [2] [3] [4] [5] .
  • SMILES
    O=S(CC(CN)C1=CC=C(Cl)C=C1)(O)=O
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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