Sacubitril

MedChem Express

Sacubitril [149709-62-6]

10

149709-62-6

Research Use Only

99.92

C24H29NO5

411.49

Sacubitril (AHU-377) is a potent and orally active NEP (neprilysin) inhibitor with an IC 50 of 5 nM. Sacubitril is a component of the heart failure medicine LCZ696. Sacubitril can be used for the research of heart failure, hypertension and COVID-19 [1] [2] [3] .

O=C(CCC(O)=O)N[C@H](CC1=CC=C(C2=CC=CC=C2)C=C1)C[C@@H](C)C(OCC)=O

-20°C,2°C to 8°C

12352200