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ProductsBack/Safinamide [133865-89-1]

Safinamide [133865-89-1]

Research Use Only
HY-70057
MedChem Express
CAS Number133865-89-1
DownloadMSDS
Product group Chemicals
Estimated Purity99.89
Molecular Weight302.34
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Safinamide [133865-89-1]
  • Delivery Days Customer
    5
  • CAS Number
    133865-89-1
  • Certification
    Research Use Only
  • Estimated Purity
    99.89
  • Molecular Formula
    C17H19FN2O2
  • Molecular Weight
    302.34
  • Scientific Description
    Safinamide is a potent, selective, and reversible monoamine oxidase B (MAO-B) inhibitor (IC50=0.098 microM) over MAO-A (IC50=580 microM)[1]. Safinamide also blocks sodium channels and modulates glutamate (Glu) release, showing a greater affinity at depolarized (IC50=8?microM) than at resting (IC50=262?microM) potentials. Safinamide has neuroprotective and neurorescuing effects and can be used for the study of parkinson disease, ischemia stroke etc.al[2][3].
  • SMILES
    O=C([C@@H](NCC1=CC=C(OCC2=CC(F)=CC=C2)C=C1)C)N
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200