Salubrinal [405060-95-9]

MedChem Express

Salubrinal [405060-95-9]

10

405060-95-9

Research Use Only

99.58

C21H17Cl3N4OS

479.80

Salubrinal is a cell-permeable and selective inhibitor of eIF2alpha dephosphorylation[1]. Salubrinal acts as a dual-specificity phosphatase 2 (Dusp2) inhibitor and suppresses inflammation in anti-collagen antibody-induced arthritis[2]. Salubrinal has antiviral activity against HSV-1 and inhibits dephosphorylation of eIF2alpha mediated by the HSV-1 protein ICP34.5[3].

O=C(NC(NC(NC1=CC=CC2=C1N=CC=C2)=S)C(Cl)(Cl)Cl)/C=C/C3=CC=CC=C3

2°C to 8°C

12352200