Bio-Connect

Salvicine [240423-23-8]

HY-W715630
MedChem Express
CAS Number240423-23-8
Product group Chemicals
Molecular Weight330.42
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Salvicine [240423-23-8]
  • Delivery Days Customer
    9
  • CAS Number
    240423-23-8
  • Certification
    Research Use Only
  • Molecular Formula
    C20H26O4
  • Molecular Weight
    330.42
  • Scientific Description
    Salvicine is a DNA topoisomerase II inhibitor (IC50=3 microM). Salvicine increases the interaction between DNA and Topo II by interacting with the ATPase domain, inhibiting DNA degradation and ATP hydrolysis. Salvicine has anticancer activities, including inhibiting Topo II, causing DNA damage, overcoming multidrug resistance, and inhibiting tumor cell adhesion[1][2].
  • SMILES
    O=C1C(C(C(C)C)=CC2=C1C(CCC(C(C)(C)O)O)=C(C)C=C2)=O
  • UNSPSC
    12352200