FACS analysis of HeLa cells using GTX83687 SAMHD1 antibody [1F6]. Red : Primary antibody Blue : Negative control antibody
![FACS analysis of HEK293T cells transfected with either SAMHD1 plasmid(Red) or empty vector control plasmid(Blue) using GTX83687 SAMHD1 antibody [1F6].](https://www.genetex.com/upload/website/prouct_img/normal/GTX83687/GTX83687_117_FACS_w_23061420_945.webp "FACS analysis of HEK293T cells transfected with either SAMHD1 plasmid(Red) or empty vector control plasmid(Blue) using GTX83687 SAMHD1 antibody [1F6].")
![WB analysis of various samples using GTX83687 SAMHD1 antibody [1F6]. Loading : 10 ug per lane Dilution : 1:200](https://www.genetex.com/upload/website/prouct_img/normal/GTX83687/GTX83687_3445_WB_w_23061420_410.webp "WB analysis of various samples using GTX83687 SAMHD1 antibody [1F6]. Loading : 10 ug per lane Dilution : 1:200")
![WB analysis of human tissues (Lane 1-Testis ; Lane 2-Omentum ; Lane 3-Uterus ; Lane 4-Breast ; Lane 5-Brain ; Lane 6-Liver ; Lane 7-Ovary ; Lane 8-Thyroid gland ; Lane 9-colon ; Lane 10-spleen) using GTX83687 SAMHD1 antibody [1F6]. Loading : 10 ug per lane Dilution : 1:200](https://www.genetex.com/upload/website/prouct_img/normal/GTX83687/GTX83687_3720_WB_w_23061420_922.webp "WB analysis of human tissues (Lane 1-Testis ; Lane 2-Omentum ; Lane 3-Uterus ; Lane 4-Breast ; Lane 5-Brain ; Lane 6-Liver ; Lane 7-Ovary ; Lane 8-Thyroid gland ; Lane 9-colon ; Lane 10-spleen) using GTX83687 SAMHD1 antibody [1F6]. Loading : 10 ug per lane Dilution : 1:200")
![WB analysis of HEK293T cells transfected with SAMHD1 plasmid (Right) or empty vector (Left) for 48 hrs using GTX83687 SAMHD1 antibody [1F6]. Loading : 5 ug per lane](https://www.genetex.com/upload/website/prouct_img/normal/GTX83687/GTX83687_3821_WB_w_23061420_914.webp "WB analysis of HEK293T cells transfected with SAMHD1 plasmid (Right) or empty vector (Left) for 48 hrs using GTX83687 SAMHD1 antibody [1F6]. Loading : 5 ug per lane")
![WB analysis of various cell lines using GTX83687 SAMHD1 antibody [1F6]. Loading : 35 ug per lane](https://www.genetex.com/upload/website/prouct_img/normal/GTX83687/GTX83687_3823_WB_w_23061420_799.webp "WB analysis of various cell lines using GTX83687 SAMHD1 antibody [1F6]. Loading : 35 ug per lane")
![ICC/IF analysis of COS7 cells transiently transfected with SAMHD1 plasmid using GTX83687 SAMHD1 antibody [1F6].](https://www.genetex.com/upload/website/prouct_img/normal/GTX83687/GTX83687_773_ICCIF_w_23061420_179.webp "ICC/IF analysis of COS7 cells transiently transfected with SAMHD1 plasmid using GTX83687 SAMHD1 antibody [1F6].")
FACS analysis of HeLa cells using GTX83687 SAMHD1 antibody [1F6]. Red : Primary antibody Blue : Negative control antibody
SAMHD1 antibody [1F6]
GTX83687
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
TargetSAMHD1
Overview
- SupplierGeneTex
- Product NameSAMHD1 antibody [1F6]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:2000. ICC/IF: 1:100. FACS: 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID1F6
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID25939
- Target nameSAMHD1
- Target descriptionSAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
- Target synonymsCHBL2, DCIP, HDDC1, MOP-5, SBBI88, hSAMHD1, deoxynucleoside triphosphate triphosphohydrolase SAMHD1, SAM domain and HD domain 1, SAM domain and HD domain-containing protein 1, dNTPase, dendritic cell-derived IFNG-induced protein, monocyte protein 5
- HostMouse
- IsotypeIgG1
- Protein IDQ9Y3Z3
- Protein NameDeoxynucleoside triphosphate triphosphohydrolase SAMHD1
- Scientific DescriptionPutative nuclease involved in innate immune response by acting as a negative regulator of the cell-intrinsic antiviral response. May play a role in mediating proinflammatory responses to TNF-alpha signaling.
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Monit C, Morris ER, Ruis C, et al. Positive selection in dNTPase SAMHD1 throughout mammalian evolution. Proc Natl Acad Sci U S A. 2019,116(37):18647-18654. doi: 10.1073/pnas.1908755116Read this paper
- Furuya AK, Sharifi HJ, Jellinger RM, et al. Sulforaphane Inhibits HIV Infection of Macrophages through Nrf2. PLoS Pathog. 2016,12(4):e1005581. doi: 10.1371/journal.ppat.1005581Read this paper
- Sharifi HJ, Furuya AK, Jellinger RM, et al. Cullin4A and cullin4B are interchangeable for HIV Vpr and Vpx action through the CRL4 ubiquitin ligase complex. J Virol. 2014,88(12):6944-58. doi: 10.1128/JVI.00241-14Read this paper
- Nekorchuk MD, Sharifi HJ, Furuya AK, et al. HIV relies on neddylation for ubiquitin ligase-mediated functions. Retrovirology. 2013,10:138. doi: 10.1186/1742-4690-10-138Read this paper
Datasheet
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