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ProductsBack/SAMHD1 antibody [1F6]
FACS analysis of HeLa cells using GTX83687 SAMHD1 antibody [1F6]. Red : Primary antibody Blue : Negative control antibody
FACS analysis of HeLa cells using GTX83687 SAMHD1 antibody [1F6]. Red : Primary antibody Blue : Negative control antibody
FACS analysis of HeLa cells using GTX83687 SAMHD1 antibody [1F6]. Red : Primary antibody Blue : Negative control antibody

SAMHD1 antibody [1F6]

GTX83687
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Monkey, Mouse
TargetSAMHD1
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Overview

  • Supplier
    GeneTex
  • Product Name
    SAMHD1 antibody [1F6] - Overexpression Validated
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:2000. ICC/IF: 1:100. FACS: 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    1F6
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID25939
  • Target name
    SAMHD1
  • Target description
    SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
  • Target synonyms
    CHBL2; DCIP; dendritic cell-derived IFNG-induced protein; deoxynucleoside triphosphate triphosphohydrolase SAMHD1; dNTPase; HDDC1; hSAMHD1; monocyte protein 5; MOP-5; SAM domain and HD domain 1; SAM domain and HD domain-containing protein 1; SBBI88
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDQ9Y3Z3
  • Protein Name
    Deoxynucleoside triphosphate triphosphohydrolase SAMHD1
  • Scientific Description
    Putative nuclease involved in innate immune response by acting as a negative regulator of the cell-intrinsic antiviral response. May play a role in mediating proinflammatory responses to TNF-alpha signaling.
  • Reactivity
    Human, Monkey, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Positive selection in dNTPase SAMHD1 throughout mammalian evolution. Monit C et al., 2019 Sep 10, Proc Natl Acad Sci U S A
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  • Sulforaphane Inhibits HIV Infection of Macrophages through Nrf2. Furuya AK et al., 2016 Apr, PLoS Pathog
    Read more
  • Cullin4A and cullin4B are interchangeable for HIV Vpr and Vpx action through the CRL4 ubiquitin ligase complex. Sharifi HJ et al., 2014 Jun, J Virol
    Read more
  • HIV relies on neddylation for ubiquitin ligase-mediated functions. Nekorchuk MD et al., 2013 Nov 18, Retrovirology
    Read more