Sanggenon C [80651-76-9]

MedChem Express

Sanggenon C [80651-76-9]

9

80651-76-9

Research Use Only

98.46

C40H36O12

708.71

Sanggenon C, a flavonoid, exerts protective effects against cardiac hypertrophy and fibrosis via suppression of the calcineurin/NFAT2 pathway. Sanggenon C inhibits mitochondrial fission to induce apoptosis by blocking the ERK signaling pathway. Sanggenon C inhibits inducible nitric oxide synthase expression in RAW264.7 cells, and TNF-alpha-stimulated cell adhesion and VCAM-1 expression, by suppressing NF-kappaB activity. Sanggenon C possesses antioxidant, anti-inflammatory and antitumor activities[1][2].

C/C(C)=C/C[C@](C1=CC=C(O)C=C1O2)(OC3=CC(O)=C([C@@H](C=C(C)C[C@@H]4C(C=CC(O)=C5)=C5O)[C@@H]4C(C(C=CC(O)=C6)=C6O)=O)C(O)=C3C7=O)[C@]27O

-20°C

12352200