Bio-Connect

Santamarine [4290-13-5]

HY-N1326
MedChem Express
CAS Number4290-13-5
Product group Chemicals
Molecular Weight248.32
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Santamarine [4290-13-5]
  • Delivery Days Customer
    10
  • CAS Number
    4290-13-5
  • Category Supplier
    CHEMICAL,general_chemicals_reagents
  • Certification
    Research Use Only
  • Molecular Formula
    C15H20O3
  • Molecular Weight
    248.32
  • Scientific Description
    Santamarine (Santamarin), a sesquiterpene lactone, increases HO-1 expression through Nrf2 translocation and suppresses NO, PGE2, TNF-alpha, and IL-1beta production through inhibition of NF-kappaB translocation in LPS-induced macrophages. Santamarine shows anti-photoaging properties via inhibition of MAPK/AP-1 and stimulation of TGF-beta/Smad signaling in UVA-irradiated human dermal fibroblasts (HDFs). Antioxidant activities[1][2].
  • SMILES
    O=C(O[C@@]1([H])[C@@]2([H])CC[C@@]3(C)[C@H](O)CC=C(C)[C@@]31[H])C2=C
  • Storage Instruction
    -20°C, 3 years (Powder)
  • UNSPSC
    12352005