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SAR1B antibody

Research Use Only
GTX109170
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetSAR1B
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Overview

  • Supplier
    GeneTex
  • Product Name
    SAR1B antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID51128
  • Target name
    SAR1B
  • Target description
    secretion associated Ras related GTPase 1B
  • Target synonyms
    2310075M17Rik; ANDD; CMRD; GTBPB; GTP-binding protein B; GTP-binding protein SAR1b; GTP-binding protein Sara; SAR1 homolog B; SAR1a gene homolog 2; SARA2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9Y6B6
  • Protein Name
    GTP-binding protein SAR1b
  • Scientific Description
    The protein encoded by this gene is a small GTPase that acts as a homodimer. The encoded protein is activated by the guanine nucleotide exchange factor PREB and is involved in protein transport from the endoplasmic reticulum to the Golgi. This protein is part of the COPII coat complex. Defects in this gene are a cause of chylomicron retention disease (CMRD), also known as Anderson disease (ANDD). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Defective endoplasmic reticulum export causes proinsulin misfolding in pancreatic beta cells. Zhu R et al., 2019 Aug 1, Mol Cell Endocrinol
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