SARAF Antibody

Cusabio

SARAF Antibody

20

ELISA

Research Use Only

Polyclonal

Unconjugated

SARAF

store-operated calcium entry associated regulatory factor

FOAP-7, HSPC035, TMEM66, XTP3, store-operated calcium entry-associated regulatory factor, HBV X-transactivated gene 3 protein, HBV XAg-transactivated protein 3, SOCE-associated regulatory factor, testicular secretory protein Li 59, transmembrane protein 66

Rabbit

IgG

Store-operated calcium entry-associated regulatory factor

Negative regulator of store-operated Ca(2+) entry (SOCE) involved in protecting cells from Ca(2+) overfilling. In response to cytosolic Ca(2+) elevation after endoplasmic reticulum Ca(2+) refilling, promotes a slow inactivation of STIM (STIM1 or STIM2)-dependent SOCE activity: possibly act by facilitating the deoligomerization of STIM to efficiently turn off ORAI when the endoplasmic reticulum lumen is filled with the appropriate Ca(2+) levels, and thus preventing the overload of the cell with excessive Ca(2+) ions.

Human

-20°C or -80°C

41116161