SARS-CoV-2 3CLpro-IN-5 [2913186-57-7]

MedChem Express

SARS-CoV-2 3CLpro-IN-5 [2913186-57-7]

10

2913186-57-7

Research Use Only

C22H26ClF2N5O4

497.92

SARS-CoV-2 3CLpro-IN-5 is a covalent inhibitor of 3C-like protease (3CLpro). SARS-CoV-2 3CLpro-IN-5 has inhibitory activity for 3CLpro with an IC50 value of 3.8 nM. SARS-CoV-2 3CLpro-IN-5 has 9.0% oral bioavailability (BA). SARS-CoV-2 3CLpro-IN-5 can be used for the research of coronavirus disease 2019 (COVID-19)[1].

FC1=CC=CC2=C1C=C(C(N[C@H](C(NN(C([C@@](F)([H])Cl)=O)C[C@H]3C(NCC3)=O)=O)CC(C)C)=O)N2

12131703