SARS-CoV-2-IN-65

MedChem Express

SARS-CoV-2-IN-65

14

Research Use Only

C22H18N2O4

374.39

SARS-CoV-2-IN-65 (compound 2f (81)) is a potent,orally active and reversible SARS-CoV-2 entry inhibitor. SARS-CoV-2-IN-65 inhibits the pseudovirus entry in a ACE2-dependent pathway, via mainly inhibiting RBD:ACE2 interaction and TMPRSS2 activity in Calu-3 cells [1] .

O=C1N(C2=CC=C(C(/C=C/C3=C4C(NC=C4)=CC=C3)=O)C=C2)CC(C(O)=O)C1

12352200