SARS-CoV-2 Mpro-IN-37

MedChem Express

SARS-CoV-2 Mpro-IN-37

5

Research Use Only

C25H30N2O3S

438.58

SARS-CoV-2 Mpro-IN-37 (compound 8r) is a SARS-CoV-2 main protease (Mpro) inhibitor, with an IC50 of 0.0199 microM. SARS-CoV-2 Mpro-IN-37 inhibits SARS-CoV-1 Mpro and MERS-CoV Mpro with IC50s of 0.00945 and 0.111 microM, respectively. SARS-CoV-2 Mpro-IN-37 displays high antiviral activity in the nanomolar range without showing cellular toxicity[1].

CC(C)C[C@H](NC(CSC1=CC=CC=C1)=O)C(N[C@H](C(C=C)=O)CC2=CC=CC=C2)=O

12352200