SARS-CoV-2 Mpro-IN-37

MedChem Express

SARS-CoV-2 Mpro-IN-37

5

Research Use Only

SARS-CoV-2 Mpro-IN-37 (compound 8r) is a SARS-CoV-2 main protease (Mpro) inhibitor, with an IC50 of 0.0199 microM. SARS-CoV-2 Mpro-IN-37 inhibits SARS-CoV-1 Mpro and MERS-CoV Mpro with IC50s of 0.00945 and 0.111 microM, respectively. SARS-CoV-2 Mpro-IN-37 displays high antiviral activity in the nanomolar range without showing cellular toxicity[1].

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