SARS-CoV-2 Mpro-IN-4

MedChem Express

SARS-CoV-2 Mpro-IN-4

10

Research Use Only

C30H38N4O5

534.65

SARS-CoV-2 Mpro-IN-4 is a dual Inhibitor of Main Protease (MPro) and Cathepsin L (CatL), with IC50s of 900 nM and 60 nM respectively. SARS-CoV-2 Mpro-IN-4 has antiviral activity against SARS-CoV2. SARS-CoV-2 Mpro-IN-4 blocks SARS-CoV2 replication in hACE2 expressing A549 cells with IC50 value of 8.2 nM[1].

CN[C@H](CC1=CC=CC=C1)C(N[C@H](C(N[C@@H](C[C@@H]2CCNC2=O)/C=C/C(OCC)=O)=O)CC3=CC=CC=C3)=O

12131703