SARS-CoV-2 Mpro-IN-4

TargetMol Chemicals

SARS-CoV-2 Mpro-IN-4

72

Chemical

Research Use Only

SARS-CoV-2 Mpro-IN-4

C30H38N4O5

534.65

SARS-CoV-2 Mpro-IN-4 is a dual inhibitor targeting Main Protease (M Pro) and Cathepsin L (CatL), with inhibition concentrations (IC50) of 900 nM and 60 nM, respectively. It effectively blocks SARS-CoV-2 replication in hACE2-expressing A549 cells, demonstrating antiviral activity with an IC50 value of 8.2 nM.

3 years

CCOC(=O)/C=C/[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@@H](CC3=CC=CC=C3)NC

-20°C

51202000