SARS-CoV-2 Mpro-IN-43

MedChem Express

SARS-CoV-2 Mpro-IN-43

999

Research Use Only

C32H41F3N2O4S2

638.80

SARS-CoV-2 Mpro-IN-43 (Compound 1) is a coronavirus main protease (Mpro) inhibitor (IC50: 72 microM). SARS-CoV-2 Mpro-IN-43 interacts with key residues in the active site of Mpro via non-covalent binding, exerting its anti-coronavirus effect. SARS-CoV-2 Mpro-IN-43 exhibits moderate to low cytotoxicity, with CC50 values of 13.24, 41.02, and 42.26 microM in HaCaT, HEK293T, and HepG2 cells, respectively. SARS-CoV-2 Mpro-IN-43 can be used in anti-SARS-CoV-2 research[1].

S=C(N1CCN(CC2=CC(F)=C(F)C=C2F)CC1)S[C@H](C3=CCOC3=O)C[C@@H]4C(CC[C@]5([H])[C@](C)(CO)[C@H](O)CC[C@@]45C)=C

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