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SARS-COV-2 Spike S Trimer Protein (D614G, His & Avi)

SARS-COV-2 Spike S Trimer Protein (D614G, His & Avi)

TMPK-00435
TargetMol Chemicals
Molecular Weight136.7 kDa (predicted). Due to glycosylation, the protein migrates to 175-230 kDa based on Tris-Bis PAGE result.
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    SARS-COV-2 Spike S Trimer Protein (D614G, His & Avi)
  • Delivery Days Customer
    16
  • Certification
    Research Use Only
  • Molecular Weight
    136.7 kDa (predicted). Due to glycosylation, the protein migrates to 175-230 kDa based on Tris-Bis PAGE result.
  • Scientific Description
    The SARS-CoV-2 spike (S) protein variant D614G supplanted the ancestral virus worldwide, reaching near fixation in a matter of months. Recently, that D614G was been found more infectious than the ancestral form on human lung cells, colon cells, and on cells rendered permissive by ectopic expression of human ACE2 or of ACE2 orthologs from various mammals, including Chinese rufous horseshoe bat and Malayan pangolin.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant. Yurkovetskiy L et al., 2020 Oct 29, Cell
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