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SARS S protein (R667A, K968P, V969P)

ORB750333
Biorbyt
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    Biorbyt
  • Product Name
    SARS S protein (R667A, K968P, V969P)
  • Delivery Days Customer
    10
  • Application Supplier Note
    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 136.3 kDa. The protein migrates as 190-210 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Certification
    Research Use Only
  • Conjugate
    Unconjugated
  • Estimated Purity
    95%
  • Scientific Description
    SARS S protein (R667A, K968P, V969P), His Tag is expressed from human 293 cells (HEK293). It contains AA Ser 14 - Pro 1195 (Accession # AAP13567.1 (R667A, K968P, V969P)). The recombinant protein is expressed with T4 fibritin trimerization motif and a polyhistidine tag at the C-terminus. Proline substitutions (K968P, V969P) and alanine substitutions (R667A) are introduced to stabilize the trimeric prefusion state of SARS-CoV S protein and abolish the furin cleavage site, respectively.
  • Source
    SARS - SARS S protein (R667A, K968P, V969P), His Tag (orb750333) is expressed from human 293 cells (HEK293). It contains AA Ser 14 - Pro 1195 (Accession # AAP13567.1 (R667A, K968P, V969P)). The recombinant protein is expressed with T4 fibritin...
  • Storage Instruction
    -20°C
  • UNSPSC
    12352202