Saruparib

MedChem Express

Saruparib [2589531-76-8]

10

2589531-76-8

Research Use Only

99.76

C22H26N6O2

406.48

Saruparib (AZD5305) is a potent, orally active and selective PARP inhibitor and trapper with IC 50 values of 3 nM and 1400 nM for PARP1 and PARP2, respectively. Saruparib has anti-proliferative activity and inhibits growth in cells with deficiencies in DNA repair [1] [2] .

O=C(C1=NC=C(N2CCN(CC3=CC(N4)=C(N=C3)C=C(CC)C4=O)CC2)C=C1)NC

-20°C,2°C to 8°C

12352200