Saterinone [102669-89-6]

TargetMol Chemicals

Saterinone [102669-89-6]

4

102669-89-6

Chemical

Saterinone

C27H30N4O4

474.55

Saterinone is a potent and selective phosphodiesterase III inhibitor and a potent antagonist of the vascular alpha-1-adrenoceptor. Saterinone has vasodilatory properties and can be used in the acute treatment of chronic heart failure. Saterinone inhibited crude cAMP phosphodiesterase (PDE) activity in guinea pig right ventricular homogenates The ic50 value is 2.3 x 10(-5) mol/l.

3 years

CC1=C(C=C(C#N)C(=O)N1)C2=CC=C(OCC(CN3CCN(CC3)C4=C(OC)C=CC=C4)O)C=C2

-20°C

12352200