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SB-1436

HY-149300
MedChem Express
Molecular Weight405.89
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Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    SB-1436 [2925298-08-2]
  • Delivery Days Customer
    14
  • Certification
    Research Use Only
  • Molecular Formula
    C25H21ClFNO
  • Molecular Weight
    405.89
  • Scientific Description
    SB-1436 is an Cholinesterase (ChE) inhibitor, inhibits acetylcholinesterase (AChE), butyrylcholinesterase (BChE) and recombinant human acetylcholinesterase (rHuAChE) with IC50s of 0.176, 0.37 and 0.08 microM, respectively. SB-1436 inhibits AChE and BChE in a non-competitive manner with Kis of 0.046 and 0.115 microM, respectively. SB-1436 significantly stops the self-aggregation of Abeta, and can be used for neurological disease research[1].
  • SMILES
    COC1=CC2=C(C=C(/C=C/C3=CC=[N+](CC4=CC=C(F)C=C4)C=C3)C=C2)C=C1.[Cl-]
  • UNSPSC
    12131703