SB-1436
HY-149300
Molecular Weight405.89
Product group Chemicals
Overview
- SupplierMedChem Express
- Product NameSB-1436 [2925298-08-2]
- Delivery Days Customer14
- CertificationResearch Use Only
- Molecular FormulaC25H21ClFNO
- Molecular Weight405.89
- Scientific DescriptionSB-1436 is an Cholinesterase (ChE) inhibitor, inhibits acetylcholinesterase (AChE), butyrylcholinesterase (BChE) and recombinant human acetylcholinesterase (rHuAChE) with IC50s of 0.176, 0.37 and 0.08 microM, respectively. SB-1436 inhibits AChE and BChE in a non-competitive manner with Kis of 0.046 and 0.115 microM, respectively. SB-1436 significantly stops the self-aggregation of Abeta, and can be used for neurological disease research[1].
- SMILESCOC1=CC2=C(C=C(/C=C/C3=CC=[N+](CC4=CC=C(F)C=C4)C=C3)C=C2)C=C1.[Cl-]
- UNSPSC12131703