SB-200646

MedChem Express

SB-200646

10

143797-63-1

Research Use Only

C15H14N4O

266.30

SB-200646 is the first selective 5-HT2B/2C over 5-HT2A receptor antagonist with pKi values of 7.5, 6.9 and 5.2 for 5-HT2B, 5-HT2C and 5-HT2A, respectively. SB-200646 is orally active and has electrophysiological and anxiolytic properties in vivo[1][2].

O=C(NC1=CC=CN=C1)NC2=CC3=C(N(C)C=C3)C=C2

12352200