SB 202190

MedChem Express

SB 202190 [152121-30-7]

10

152121-30-7

Research Use Only

99.89

C20H14FN3O

331.34

SB 202190 is a selective p38 MAP kinase inhibitor with IC 50 s of 50 nM and 100 nM for p38alpha and p38beta2, respectively. SB 202190 binds to the ATP pocket of the active recombinant human p38 kinase with a K d of 38 nM. SB 202190 has anti-cancer activity and rescued memory deficits [1] [2] . SB202190 induces autophagy [3] .

FC1=CC=C(C2=C(C3=CC=NC=C3)NC(C4=CC=C(O)C=C4)=N2)C=C1

-20°C,2°C to 8°C

12352200