SB 202190 (hydrochloride)

MedChem Express

SB 202190 (hydrochloride)

10

350228-36-3

Research Use Only

99.66

C20H15ClFN3O

367.80

SB 202190 hydrochloride is a selective p38 MAP kinase inhibitor with IC50s of 50 nM and 100 nM for p38alpha and p38beta2, respectively. SB 202190 hydrochloride binds to the ATP pocket of the active recombinant human p38 kinase with a Kd of 38 nM. SB 202190 hydrochloride has anti-cancer activity[1][2]. SB202190 hydrochloride induces autophagy[3].

OC1=CC=C(C2=NC(C3=CC=C(F)C=C3)=C(C4=CC=NC=C4)N2)C=C1.[H]Cl

-20°C

12352200