SB 202190 (hydrochloride)

MedChem Express

SB 202190 (hydrochloride) [350228-36-3]

10

350228-36-3

Research Use Only

99.84

C20H15ClFN3O

367.80

SB 202190 hydrochloride is a selective p38 MAP kinase inhibitor with IC 50 s of 50 nM and 100 nM for p38alpha and p38beta2, respectively. SB 202190 hydrochloride binds to the ATP pocket of the active recombinant human p38 kinase with a K d of 38 nM. SB 202190 hydrochloride has anti-cancer activity [1] [2] . SB202190 hydrochloride induces autophagy [3] .

OC1=CC=C(C2=NC(C3=CC=C(F)C=C3)=C(C4=CC=NC=C4)N2)C=C1.[H]Cl

-20°C

12352200