SB 218795

MedChem Express

SB 218795 [174635-53-1]

10

174635-53-1

Research Use Only

99.86

C25H20N2O3

396.44

SB 218795 is a potent and selective non-peptide NK3 receptor antagonist, with a K i 13 nM for hNK3 . SB 218795 shows about 90-fold and 7000-fold selectivity for hNK3 over hNK2 and hNK1, respectively. SB 218795 can inhibit NK3 receptor-mediated pupillary constriction of the rabbit [1] [2] .

COC([C@@H](C1=CC=CC=C1)NC(C2=CC(C3=CC=CC=C3)=NC4=CC=CC=C24)=O)=O

-20°C,2°C to 8°C

12352200