SB-236057 [180083-49-2]
HY-116603
CAS Number180083-49-2
Product group Chemicals
Molecular Weight534.65
Overview
- SupplierMedChem Express
- Product NameSB-236057 [180083-49-2]
- Delivery Days Customer9
- CAS Number180083-49-2
- CertificationResearch Use Only
- Molecular FormulaC33H34N4O3
- Molecular Weight534.65
- Scientific DescriptionSB-236057 is an inverse agonist of the 5-HT1B receptor that exhibits strong skeletal teratogenicity in rodents and rabbits. SB-236057 affects gene expression during embryonic development through interference with the Notch signaling pathway and interaction with r-esp1. SB-236057 induces somatic patterning and tail extension defects in rat embryos during early organogenesis[1].
- SMILESO=C(N1C2=CC3=C(C=C2CC1)OCC34CCN(CC4)CC)C5=CC=C(C6=C(C)C=C(C7=NN=C(C)O7)C=C6)C=C5
- UNSPSC12352200