SB-265610 [211096-49-0]

MedChem Express

SB-265610 [211096-49-0]

10

211096-49-0

Research Use Only

99.0

C14H9BrN6O

357.16

SB-265610 is a selective, competitive, nonpeptide and allosteric CXCR2 antagonist. SB-265610 blocks rat cytokine-induced neutrophil chemoattractant-1 (CINC-1)-induced calcium mobilization and neutrophil chemotaxis with IC50s of 3.7 nM and 70 nM, respectively[1][2].

N#CC1=C(N=NN2)C2=C(C=C1)NC(NC(C=CC=C3)=C3Br)=O

-20°C,2°C to 8°C

12352200