SB-423557 [351490-26-1]

MedChem Express

SB-423557 [351490-26-1]

10

351490-26-1

Research Use Only

C28H36N2O4

464.60

SB-423557 is an orally active calcium-sensing receptor (CaR) antagonist (IC50=520 nM), precursor of SB-423562 (IC50=73 nM). SB-423557 is well tolerated in human and increases plasma concentrations of exogenous parathyroid hormone (PTH) and stimulates bone formation[1].

O=C(OCC)CCC1=CC=C(C#N)C(OC[C@H](O)CNC(C)(C)CC2CC3=C(C=CC=C3)C2)=C1

12131703