SB-505124 [694433-59-5]

MedChem Express

SB-505124 [694433-59-5]

10

694433-59-5

Research Use Only

99.73

C20H21N3O2

335.40

SB-505124 is a selective inhibitor of TGF-beta Receptor type I receptors (ALK4, ALK5, ALK7), with IC50s of 129 nM and 47 nM for ALK4, ALK5, respectively, but it does not inhibit ALK1, 2, 3, or 6.

CC1=CC=CC(C2=C(C3=CC=C(OCO4)C4=C3)N=C(C(C)(C)C)N2)=N1

-20°C,2°C to 8°C

12352200