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SB 525334

T1763
TargetMol Chemicals
CAS Number356559-20-1
Product group Chemicals
Molecular Weight343.42
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    SB 525334
  • Delivery Days Customer
    4
  • CAS Number
    356559-20-1
  • Category Supplier
    Chemical
  • Chemical Name
    SB 525334
  • Molecular Formula
    C21H21N5
  • Molecular Weight
    343.42
  • Scientific Description
    SB-525334 is a potent and selective inhibitor of the TGF-bèta1R and ALK5 (IC50: 14.3 nM).
  • Shelf life instruction
    3 years
  • SMILES
    C(C)(C)(C)C=1NC(=C(N1)C=2N=C(C)C=CC2)C3=CC4=C(C=C3)N=CC=N4
  • Storage Instruction
    -20°
  • UNSPSC
    12352200

References

  • Grygielko ET, et al. Inhibition of gene markers of fibrosis with a novel inhibitor of transforming growth factor-beta type I receptor kinase in puromycin-induced nephritis. J Pharmacol Exp Ther. 2005 Jun;313(3):943-51.
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