SB-674042

MedChem Express

SB-674042 [483313-22-0]

10

483313-22-0

Research Use Only

99.93

C24H21FN4O2S

448.51

SB-674042 is a potent and selective non-peptide orexin OX 1 receptor antagonist (K d =5.03 nM), exhibits 100-fold selectivity for OX 1 over OX 2 receptors with IC 50 values of 3.76 nM and 531 nM, respectively [1] [4] .

FC1=C(C2=C(C(N3[C@H](CC4=NN=C(C5=CC=CC=C5)O4)CCC3)=O)N=C(C)S2)C=CC=C1

-20°C,2°C to 8°C

12352200