SB-674042 [483313-22-0]

MedChem Express

SB-674042 [483313-22-0]

10

483313-22-0

Research Use Only

99.93

C24H21FN4O2S

448.51

SB-674042 is a potent and selective non-peptide orexin OX1 receptor antagonist (Kd=5.03 nM), exhibits 100-fold selectivity for OX1 over OX2 receptors with IC50 values of 3.76 nM and 531 nM, respectively[1][4].

FC1=C(C2=C(C(N3[C@H](CC4=NN=C(C5=CC=CC=C5)O4)CCC3)=O)N=C(C)S2)C=CC=C1

-20°C,2°C to 8°C

12352200