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Chemical Structure
Chemical Structure
Chemical Structure

SB204990 [154566-12-8]

AG-CR1-3697
AdipoGen Life Sciences
CAS Number154566-12-8
Product group Chemicals
Estimated Purity>95%
Molecular Weight389.3
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    SB204990
  • Delivery Days Customer
    10
  • CAS Number
    154566-12-8
  • Certification
    Research Use Only
  • Estimated Purity
    >95%
  • Molecular Formula
    C18H22Cl2O5
  • Molecular Weight
    389.3
  • Scientific Description
    Chemical. CAS: 154566-12-8. Formula: C18H22Cl2O5. MW: 389.3. Potent ATP citrate lyase (ACLY) inhibitor. ATP citrate lyase (ACLY), a key enzyme for lipid synthesis, is frequently overexpressed or activated in cancer to promote lipid synthesis and tumor progression. Cell permeable prodrug form of SB201076. Hypolipidemic agent. Fatty acid synthesis and cholesterol synthesis inhibitor in a dose-dependent manner. Useful agent for immunometabolism research. Orally active in vivo. Shown to block fatty acid synthesis and cancer cell growth in pre-clinical studies. - Potent ATP citrate lyase (ACLY) inhibitor. ATP citrate lyase (ACLY), a key enzyme for lipid synthesis, is frequently overexpressed or activated in cancer to promote lipid synthesis and tumor progression. Cell permeable prodrug form of SB201076. Hypolipidemic agent. Fatty acid synthesis and cholesterol synthesis inhibitor in a dose-dependent manner. Useful agent for immunometabolism research. Orally active in vivo. Shown to block fatty acid synthesis and cancer cell growth in pre-clinical studies.
  • SMILES
    O=C1[C@](CC(O)=O)(O)C[C@@H](CCCCCCC2=CC=C(Cl)C=C2Cl)O1
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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