SBI-0640726
HY-164524
Molecular Weight386.83
Product group Chemicals
Overview
- SupplierMedChem Express
- Product NameSBI-0640726
- Delivery Days Customer9
- CertificationResearch Use Only
- Molecular FormulaC23H15ClN2O2
- Molecular Weight386.83
- Scientific DescriptionSBI-0640726 is an eIF4G1 inhibitor with antiproliferative activity in melanoma. SBI-0640726 disrupts the eIF4F translation initiation complex by inhibiting AKT and NF-kB signaling pathways. SBI-0640726 inhibits the growth of NRAS and BRAF mutant melanoma in vitro[1].
- SMILESO=C(C1=C(C2=CC=CC=C2)C3=C(C=CC(Cl)=C3)NC1=O)/C=C/C4=CC=CC=N4
- UNSPSC12352200