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ProductsBack/SBI-797812 [2237268-08-3]

SBI-797812 [2237268-08-3]

Research Use Only
HY-126255
MedChem Express
CAS Number2237268-08-3
DownloadMSDS
Product group Chemicals
Estimated Purity99.74
Molecular Weight402.47
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Overview

  • Supplier
    MedChem Express
  • Product Name
    SBI-797812 [2237268-08-3]
  • Delivery Days Customer
    10
  • CAS Number
    2237268-08-3
  • Certification
    Research Use Only
  • Estimated Purity
    99.74
  • Molecular Formula
    C19H22N4O4S
  • Molecular Weight
    402.47
  • Scientific Description
    SBI-797812 is an orally active nicotinamide phosphoribosyltransferase (NAMPT) activator. SBI-797812 shifts NAMPT to NMN formation, increases NAMPT affinity for ATP, stabilizes phosphorylated NAMPT, promotes consumption of the pyrophosphate by-product, and blunts feedback inhibition by NAD+. SBI-797812 increases intracellular nicotinamide mononucleotide (NMN) and elevates liver NAD+ in mice[1][2].
  • SMILES
    O=C(NCC1=CC=NC=C1)NC2=CC=C(S(=O)(N3CC(O4)CCC4C3)=O)C=C2
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200