sbp-7455 [1884222-74-5]
T8850
CAS Number1884222-74-5
Product group Chemicals
Estimated Purity99.03%
Molecular Weight354.33
Overview
- SupplierTargetMol Chemicals
- Product Namesbp-7455 [1884222-74-5]
- Delivery Days Customer4
- CAS Number1884222-74-5
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical Namesbp-7455
- Estimated Purity99.03%
- Molecular FormulaC16H17F3N4O2
- Molecular Weight354.33
- Scientific DescriptionSBP-7455 potently inhibited ULK1/2 enzymatic activity in vitro and in cells, reduced the viability of TNBC cells and had oral bioavailability in mice.
- Shelf life instruction3 years
- SMILESCOc1ccc(Nc2ncc(c(NC3CC3)n2)C(F)(F)F)cc1OC
- Storage Instruction-20°C
- UNSPSC12352200
References
- Design, Synthesis, and Characterization of an Orally Active Dual-Specific ULK1/2 Autophagy Inhibitor that Synergizes with the PARP Inhibitor Olaparib for the Treatment of Triple-Negative Breast Cancer. Ren H et al., 2020 Dec 10, J Med ChemRead more
