SC144
HY-15614
Overview
- SupplierMedChem Express
- Product NameSC144 [895158-95-9]
- Delivery Days Customer10
- CAS Number895158-95-9
- CertificationResearch Use Only
- Estimated Purity99.48
- Molecular FormulaC16H11FN6O
- Molecular Weight322.30
- Scientific DescriptionSC144 is a first-in-class, orally active gp130 (IL6-beta) inhibitor. SC144 binds gp130, induces gp130 phosphorylation (S782) and deglycosylation, abrogates Stat3 phosphorylation and nuclear translocation, and further inhibits the expression of downstream target genes. SC144 shows potent inhibition of gp130 ligand-triggered signaling. SC144 induces apoptosis in human ovarian cancer cells[1].
- SMILESO=C(C1=NC=CN=C1)NNC2=NC3=C(N4C2=CC=C4)C=CC(F)=C3
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200
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Product group Chemicals
SC144ORB1300980
CAS Number895158-95-9
Estimated Purity99.85%
Molecular Weight322.3
- SizePrice
![SC144 [895158-95-9]](https://www.targetmol.com/group3/M00/37/E9/CgoaEWayU7eEZcNRAAAAADW7-vQ135.png)
Product group Chemicals
SC144 [895158-95-9]T6207
CAS Number895158-95-9
Estimated Purity99.85%
Molecular Weight322.3
- SizePrice