SCH-23390 (hydrochloride)

MedChem Express

SCH-23390 (hydrochloride) [125941-87-9]

10

125941-87-9

Research Use Only

99.77

C17H19Cl2NO

324.24

SCH-23390 hydrochloride (R-(+)-SCH-23390 hydrochloride) is a potent and selective dopamine D 1 -like receptor antagonist with K i s of 0.2 nM and 0.3 nM for the D 1 and D 5 receptor , respectively. SCH-23390 hydrochloride is a potent and high efficacy human 5-HT 2C receptor agonist with a K i of 9.3 nM. SCH-23390 hydrochloride also binds with high affinity to the 5-HT 2 and 5-HT 1C receptors . SCH-23390 hydrochloride inhibits G protein-coupled inwardly rectifying potassium (GIRK) channels with an IC 50 of 268 nM [1] [2] [3] .

OC1=C(Cl)C=C2CCN(C)C[C@H](C3=CC=CC=C3)C2=C1.[H]Cl

2°C to 8°C

12352200