SCH 351591 [444659-43-2]

MedChem Express

SCH 351591 [444659-43-2]

5

444659-43-2

CHEMICAL,general_chemicals_reagents

Research Use Only

C17H10Cl2F3N3O3

432.18

SCH 351591 is a potent, selective and orally active phosphodiesterase-4 (PDE4) inhibitor with an IC50 of 58 nM. SCH 351591 can inhibit all 4 PDE4 subtypes (A, B, C, and D). SCH 351591 has the potential for the asthma and chronic obstructive pulmonary disease (COPD) research[1].

O=C(C1=C2C=CC(C(F)(F)F)=NC2=C(OC)C=C1)NC3=C(Cl)C=[N+]([O-])C=C3Cl

-20°C, 3 years; 4°C, 2 years (Powder)

12352005