SCH-42354 [144505-58-8]
HY-106975
CAS Number144505-58-8
Product group Chemicals
Molecular Weight341.49
Overview
- SupplierMedChem Express
- Product NameSCH-42354 [144505-58-8]
- Delivery Days Customer10
- CAS Number144505-58-8
- CertificationResearch Use Only
- Molecular FormulaC16H23NO3S2
- Molecular Weight341.49
- Scientific DescriptionSCH-42354 is a potent, orally active neutral endopeptidase (NEP) inhibitor, is the pharmacologically active form of the proagent SCH-42495. SCH-42354 inhibits the hydrolysis of NEP to enhance the activity of atrial natriuretic peptide (ANP). SCH-42354 inhibits hydrolysis of leu-enkephalin and ANF with IC50 values of 8.3 nM and 10.0 nM, respectively. SCH-42354 has antihypertensive activity[1][2].
- SMILESCSCC[C@@H](C(O)=O)NC([C@@H](CS)CC1=C(C=CC=C1)C)=O
- UNSPSC12352200