SCH772984

MedChem Express

SCH772984 [942183-80-4]

10

942183-80-4

Research Use Only

99.83

C33H33N9O2

587.67

SCH772984 is a highly selective and ATP-competitive ERK inhibitor, with IC50s of 4 and 1 nM for ERK1 and ERK2, respectively. SCH772984 has antitumor activity in MAPK inhibitor-na ve and MAPK inhibitor-resistant cells containing BRAF or RAS mutations[1].

O=C([C@H](CC1)CN1CC(N(CC2)CCN2C(C=C3)=CC=C3C4=NC=CC=N4)=O)NC5=CC6=C(C=C5)NN=C6C7=CC=NC=C7

-20°C,2°C to 8°C

12352200